Vitamin C and Gout

Gout and Vitamin C

Fight gout with this popular vitamin

The connection between gout and Vitamin C has been the subject of a few studies over the past 30 years. You may have read in the news about a recent New Zealand study about Vitamin C and gout. The study claims that taking vitamin C supplements daily doesn’t lower uric acid levels as much as drugs do. This is a study that only evaluated 40 people for about 8 weeks! Is this study supposed to debunk the other 20 year study of nearly 47,000 men (done between 1986 and 2006) taking vitamin C supplements which showed to decrease uric acid levels and ease inflammation of gout sufferers? Hmm…I wonder if Big Pharma had anything to do with this study getting so much publicity? Gotta push that Colchicine and Allopurinol, we got the quarterly report coming up and we must boost sales and profit!

In the same study from the Boston University School of Medicine, 1317 men, developed gout during this 20 year period. The study found that those who took 1,000mg to 1,499mg per day had a 34% lower risk of gout and those who took 1,500mg per day had a 45% lower risk. Note that this was irrespective of other gout risk factors such as diet and alcohol use.

The lowdown on the latest vitamin C study and gout.

Going back to our original study that came out a couple months ago, the researchers split 2 groups of 20 people with gout, the first group was already taking allopurinol and the second group were not. The first group was told to either increase their dose of the medicine or also take 500 milligrams of vitamin C supplements every day. The second group who were not already taking medication were either started on allopurinol or told to take a 500mg vitamin C supplement every day.

At the beginning of the 8 week study, the of uric acid levels in the patients’ blood was 9 mg per decilitre on average. The researchers said a healthy uric acid level falls below 6.5 mg per decilitre. In both cases, patients who started taking vitamin C, with or without allopurinol, did not see a significant decrease in uric acid levels. There was, however, a significant decrease in the uric acid levels of the patients who started on allopurinol, about 3 mg per decilitre and in those who were on the drug but increased their doses, about 1.6 milligrams per decilitre decrease, the study claimed.

Tart Cherry Extract for Gout

At the end the researchers concluded that vitamin C had no effect but this was quickly dismissed by Dr. Tim Bongartz, a rheumatologist from the Mayo Clinic in Rochester, Minnesota, who basically said that it’s difficult to make any firm conclusions from the new study, because it would take about 200 participants in each group to see a difference. He also added that even if the study could reproduce the results of past studies of people without gout, it probably wouldn’t bring people’s uric acid levels below the threshold of 6.5 milligrams per decilitre and it doesn’t mean medication is the only answer.

Dr. Bongartz went on to say that there are other measures that can help gout sufferers drop their uric acid levels and the most important one being for obese individuals to lose weight. At the end fellow gout sufferer, it is you that must discern, properly breaking down the evidence and make your own decision on what to believe is fact or fiction from the information provided here. Don’t take my word for any of the information and recommendations provided by myself on this website, do your own homework and make your own conclusions from the information you process.

What are the benefits of vitamin C?

Now let’s take a closer look at vitamin C, it has many health benefits which include boosting your immune system, helps us detoxify, protects against cardiovascular disease, helps with good bacteria in the gut, eye disease, removes heavy metals from our bodies and many other benefits. Try to include it in your diet from fresh raw foods like oranges, cantaloupe, broccoli, red peppers, chili peppers, rose hips, parsley, kiwi fruit but make sure all of that stuff is organic! I personally take a supplement of vitamin C daily of 500mg and have been for years now, I buy the big bottle from Costco’s brand Kirkland, lasts me for 500 days!

Remember vitamin C is an essential nutrient for humans and certain other animal species. Remember, that vitamins and drugs operate in 2 different ways in order to reduce uric acid levels. Drugs like allopurinol restricts its’ supply by inhibiting purine breakdown into uric acid and vitamins like vitamin C improve uric acid’s excretion in the urine. Improving excretion may be more important for you than lowering production.

I’m not saying Vitamin C is a cure-all for gout but when combined with other vitamins for gout, a low purine diet and the other natural remedies for gout described elsewhere on this website, it could be very useful, my fellow gout sufferer. If you do take vitamin C, make sure to drink plenty of water and check your urine pH regularly to avoid excess acidity or you can take an Ester-C version of Vitamin C, because it is non-acidic.

Posted by Spiro Koulouris

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  • Luc

    Reply Reply July 4, 2018

    00mg of vitamin C is just a joke, as it were many times demonstrated through plenty of studies across those last 60 years. To be efficient, treatment needs megadoses of vitamin C, at least 20-30gr/day. Refer to studies made by Dr Frederick Klenner to see what means megadoses.

  • Ruth Knight

    Reply Reply February 18, 2018

    I have 3 questions.
    Are gout flare-ups exacerbated by eating refined carbs and sugar (think apple pie for breakfast, pasta etc.)?
    Is naturally occurring fructose bad for gout (bananas, pears, oranges etc.)
    What do you think of the ketogenic diet as useful in preventing flare-ups?
    Thank you

    • Spiro Koulouris

      Reply Reply February 19, 2018

      Hi Ruth!

      Yes refined sugars get processed from liver and kidneys and will raise uric acid. If you eat pasta, all you have to do is choose 100% whole grain.

      Naturally occurring fructose is obviously a tad better but still keep your portions limited. Have just 1 fruit a day if you can.

      As for Ketogenic diet, I’m not a fan, I think it’s just a fad that will go away. Look at the Gluten-Free movement, past 2 years there has been a huge decline and will probably disappear in a few years. You can learn more on my post about Gout and Ketogenic Diet.

  • George Schulte

    Reply Reply February 2, 2018

    It is also important to note that Allupurinol inhibits the conversion of purines into Uric acid. However, that is one of the paths to expel purines from the body. If purines are not expelled from the body via the uric acid path, it still accumulates in the body and is stored in the liver. Not a solution!

  • Roger

    Reply Reply October 11, 2017

    I’ve had occasional gout attacks for years despite taking 500mg vitamin C a day. I stopped taking vitamin C in January but noticed a significant increase in gout attacks, something like every 2 or 3 weeks. Six months later I read that vitamin C might be good for gout so started taking it again and I haven’t had an attack in the 4 months since. So, I would say there is definitely a link for me.

  • Cohn

    Reply Reply September 23, 2017

    I have suffered gout attacks since the mid 1990’s usually 4 to 6 per year. I tried everything, tart cherry juice, quit drinking beer, was even a vegetarian for 3 years. Even living like a monk I still would experience attacks.

    I had relied on indocin to get me through attacks but my joints were stiff and swollen even when I wasn’t having an attack. I live in Florida and my work has allowed me to wear flip flops. Shoes have been pretty much out of the question for years.

    During my most recent attack I had begun taking vitamin C for another reason and I noticed my gout changed a little. I felt an itching as you do when a wound is healing and my toe had much less pain to the touch. I tried 1000mg of drug store C twice a day and noticed even more difference. So I went for it and ordered vitamin C crystals. I now take 1 tsp (4000mg) twice a day in water buffered with one half tsp baking soda.

    I haven’t had an attack in 5 months. What is really different is my swelling is gone and I can curl my toes, wear shoes and if I happen to hit my foot there is no extreme pain like I have had for years.

    So there you have it. I know 5 months is not long but I feel completely different.

  • Graham

    Reply Reply April 23, 2017

    Hi Spiro!

    I have been told that mandarins are detrimental for a person with gout. I was wondering if you could tell me if this is correct?

    Thank you

    • Spiro Koulouris

      Reply Reply April 23, 2017

      Hi Graham!

      No that is first I hear about it. You can eat mandarins, I eat them in winter and enjoy their vitamin C which helps your gout.

  • Cameron

    Reply Reply April 17, 2017

    My gout is caused by Vitamin C ‘Capsules’
    (the ones that you dissolve in water)
    I know this by self monitoring of all foods.
    Takes time but worth it.
    96% of ALL arthritis is caused by diet and is
    associated with your DNA factor, North or South
    hemisphere family roots and climate.
    Remember this…. Gout is a type of Arthritis.

    Best wishes.


  • Tim Dunn

    Reply Reply April 26, 2015

    500 mg of vitamin C a day just isn’t enough to treat gout. Take at least a 1000 mg (1 gram,) a day of vitamin C, and take it in a buffered, time release form, so that the acid doesn’t hurt your digestive system. Use the vitamin C as a booster for your daily allopurinal, when it’s not quite doing the job. I find that a high load of allergens, such as wind bourne pollen in spring, increases all rheumatic disorders, including gout, psoriasis, anklyosing spondylitis, rheumatoid arthritis, and other allergies and auto-immune disorders. Other diet based treatments will help your drug regimen, such as cold water fish oil extracts with omega 3 fatty acids, and nature’s antioxidants such as compounds from grape seeds and grape skins – resveratrol, polyphenols and flavanols. Take these natural treatments along with the scientific medicines such as NSAIDS. Any natural antioxidant will also help, such as over the counter alpha lipoic acid and astaxanthin. Bright red and bright blue fruit contain many helpful compounds that are anti-oxidant.

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