Un regard complet sur les médicaments contre la goutte
Si vous souffrez de la goutte, votre médecin peut traiter votre affection à l'aide de deux types de médicaments. Tout d'abord, il y a les médicaments préventifs de la goutte, que vous prenez quotidiennement pour maintenir les niveaux d'acide urique normaux, et les médicaments qui vous aident lors des crises de goutte, lorsque vous êtes le plus en douleur, mal à l'aise et que vous cherchez un soulagement.
Le médicament que votre médecin vous recommandera dépendra de votre état de santé actuel et de vos préférences personnelles. Il est fort probable que votre médecin combinera une option à court terme et une option à long terme pour des résultats optimaux. Les médicaments contre la goutte sont divisés en deux catégories : à court terme ou à long terme.
Les médicaments à court terme traiteront votre crise de goutte en vous fournissant un soulagement de la douleur et une réduction de l'inflammation de l'articulation affectée. Dans le même temps, ils peuvent empêcher une autre crise de se produire. Avec ces médicaments, une fois que vous avez pris la première dose, vous pouvez généralement vous attendre à un soulagement de vos symptômes dans les 24 heures suivant l'utilisation. Votre médecin vous prescrira généralement un médicament qui sera utilisé pendant une courte période, pas plus d'une semaine.
La liste des médicaments à court terme comprend les éléments suivants :
- Colchicinele médicament le plus efficace pour soulager la douleur, conçu pour bloquer l'inflammation et réduire l'enflure causée par les cristaux d'acide urique logés dans votre (vos) articulation(s). Elle se présente sous forme de comprimé et porte le nom de marque Colcrys. Colchicine a également été démontrée pour réduire les crises de goutte de 85 % !Ainsi, si vous sentez qu'une crise est en train de se produire, c'est un moyen efficace d'arrêter une attaque douloureuse de goutte potentielle. Les doses faibles de colchicine sont généralement bien tolérées, mais des doses plus élevées peuvent entraîner des effets secondaires tels que des nausées, des vomissements et de la diarrhée.
- Les anti-inflammatoires non stéroïdiens (AINS) :: AINS les AINS sont des médicaments anti-inflammatoires disponibles en vente libre (Motrin, Advil et Aleve) dans votre pharmacie locale, et si vous souhaitez des doses plus élevées, ils ne seront disponibles que sur ordonnance de votre médecin (Celebrex, Indocin, Anaprox et Volatren). Ils se présentent sous forme de comprimé ou de capsule qui peut être prise par voie orale et peuvent également être disponibles sous forme de gel topique. Les AINS réduiront la douleur et l'enflure en bloquant les enzymes et les protéines impliquées dans le processus inflammatoire. Les effets secondaires peuvent inclure des nausées, des éruptions cutanées, des urticaires et même des brûlures d'estomac.
- CorticostéroïdesSi vous ne pouvez pas tolérer les AINS ou la colchicine, c'est votre dernière option. Selon le médicament, ils peuvent être pris sous forme de comprimé ou injectés dans le muscle où l'articulation est affectée. La prednisone est le corticostéroïde le plus couramment prescrit. Les corticostéroïdes aideront à réduire la douleur et l'enflure de l'inflammation, offrant un soulagement presque immédiat des symptômes de la goutteNotez que si vous êtes diabétique, vous pouvez rencontrer des changements dans votre taux de sucre dans le sang lors de la prise de corticostéroïdes.
Les médicaments à long terme pour la goutte ne sont prescrits que lorsque des analyses de sang ont été effectuées et ont confirmé que vous souffrez d'hyperuricémie et/ou de niveaux élevés d'acide urique. Ces médicaments agissent pour maintenir des niveaux d'acide urique sains et prévenir toute future crise ou attaque de goutte. Il convient de noter de ne pas prendre ces médicaments pendant une crise de goutte. Prendre l'un de ces médicaments pendant une crise de goutte peut aggraver votre état.
La liste des médicaments à long terme pour la goutte comprend les éléments suivants :
- l'AllopurinolGénéralement considéré comme le saint Graal des médicaments contre la goutte, l'allopurinol est un inhibiteur de la xanthine oxydase, ce qui signifie qu'il inhibe l'activité de la xanthine oxydase, une enzyme impliquée dans la métabolisation des purines par votre corps, réduisant ainsi la production d'acide urique. Il est commercialisé sous le nom de marque Zyloprim ou Lopurin allopurinol et peut prendre jusqu'à six mois pour agir chez certains patients. Vous pouvez donc éprouver des poussées pendant cette période.
- le fébuxostatil fonctionne de la même manière que l'allopurinol en réduisant les niveaux d'acide urique dans le sang. le fébuxostat Le febuxostat est commercialisé sous le nom de marque Uloric. Il est métabolisé par le foie, il est donc considéré comme sûr pour les personnes souffrant d'une maladie rénale.
- Probenécide:est commercialisé sous les noms de marque Benemid et Probalan, il agit comme un médicament préventif en réduisant l'acide urique. Il est principalement prescrit aux personnes souffrant de goutte dont les reins n'éliminent pas correctement l'acide urique, le probénécide peut les aider à augmenter leur excrétion.
- Lesinurad :est commercialisé sous le nom de marque Zurampic et est le petit nouveau dans la réduction des niveaux d'acide urique dans le sang. Il est souvent utilisé en combinaison avec l'allopurinol pour traiter la goutte chez les patients qui ne peuvent pas atteindre leurs objectifs d'acide urique avec seulement l'allopurinol.
- Pegloticasec'est un médicament pour environ 3% de la population atteinte de goutte qui sont intolérants à toutes les autres options de traitement. Il est administré par perfusion intraveineuse toutes les deux semaines et est considéré comme une option de dernier recours. Il est commercialisé sous le nom de marque Krystexxa.
La vérité est, et vous savez qui vous êtes (parce que j'ai été personnellement coupable de cela aussi), que de nombreux patients souffrant de la goutte, après avoir été épargnés d'une crise ou d'une poussée pendant une longue période, se demanderont s'ils doivent continuer à prendre leur médicament. Rien ne se produira d'abord, mais après un certain temps, une crise de goutte vous frappera. Sans traitement, des crises futures sont susceptibles de se produire et d'être plus graves.
Suivre un régime alimentaire spécifique à la goutte et un changement de mode de vie (un régime spécifique aux personnes souffrant de la goutte comme décrit dans mon livre électronique et sur ce site Web) est également impératif ! Certains d'entre vous pourront arrêter leur médication, tandis que d'autres ne le pourront pas. Pour l'instant, il n'y a pas de remède pour traiter la goutte de façon permanente, c'est pourquoi les changements alimentaires et les changements de mode de vie sont si importants pour éviter l'aggravation de votre état.
33 replies to "Médicaments contre la goutte"
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I read all the comments and was curious as why there are no supplements being recommended. I have tried cherry juice and it had no effect on my Uric acid levels. Are all these supplements ineffective?
Supplements are meant to supplement your diet. It doesn’t mean you can eat what you want and take NutriGout for example and think your gout will be gone. You have to eat well and supplement where a gout sufferer is weakest (the kidneys) and supplement with ingredients that are help cleanse the kidneys for example, what NutriGout does. There are many other articles that recommend NutriGout and other supplements we offer.
Hi. My husband is a gout sufferer. He is now 33yo and has had gout since he was 19. In the past he had been successful in a diet and exercise to reduce the attacks (that lasted about 1yr). He has been prescribed Allopurinol, Colchine (Colcrys), Indocin 75mg.
This recent flare up has by far last the longest (4wks). He’s currently unable to move and has been in bed pretty much majority of this attack. Hoping that I am able to get him medical care soon, I came across your website while doing research.
My concern at this point, because he has taken his indoncin this whole time it’s not effective and has not relieved any of the attack thus far. From my understanding, 75mg is the highest dosage Indocin comes and have not been introduced to any news in meds.
Do you know of any other stronger meds that are available? He’s had the quick fix urgent care injection of predisone multiple times in the past. But I’ve been told that also deteriorates the bone cartilage. This disease has been stressful for both myself and of course for my husband. Any advice or suggestions are greatly appreciated. I’ve heard him say many times in the past, his lifestyle of bad eating and heavy drinking will stop. And being that this is the longest run we’ve had to face, of course it’s the same song. At this point all I do is pray to God that this too will pass.
Sorry to hear Deborah.
Unfortunately only a doctor can help him. I would recommend he seeks the advice of 2 qualified rheumatologists and takes it from there. I don’t provide any advice on medication, I only provide nutritional advice. I am surprised Colchicine is not working. Has his doctor recommended a higher dose? If he is suffering, he should be taking colchicine but at a higher dose until the inflammation subsides. For long term uric acid reduction, ask his doctor about febuxostat. If allopurinol is not working then he can try febuxostat.
Good luck!
Hi!
I have this gout pain for about 2 weeks now. I have been taking puricos 300 and in vane as nothing has happened. I had decided to go to the doctor yesterday and received all the necessary injection my toe was starting to feel better but now it seems as if the problem is back to square one. Any suggestions?
Hello,
I have a big thopi on my elbow and thinking of getting rid of it without a surgery.
Does anyone have an experience with pegloticase treatment? How long does it take? How much it cost? and is there a side impact?
Hi there!
I am currently in the middle of one of my more painful gout attacks and the joint on my foot and big toe has become discolored and bruised. Is this something you’ve come across?
I went to emergency today and they perscribed me colchicine, which I have never been perscribed before and hopefully it clears it out.
Hi Clayton!
Yes colchicine works best to get rid of the pain and inflammation. It also works fast, usually within a few days.
Wish you a speedy recovery!
Thanks for the web site, I’ve had gout for about 10 years and for the first 2 years it was undiagnosed by 3 different doctors. I was given a powerful opioid for the pain which did not help at all. I now feel like I know a lot about my gout, and I think it’s true that every person is different so it’s important to get individual medical advice from a doctor who knows about gout. Most doctors really don’t know much. My personal magic bullet is prednisone which I have on hand at all times. If I take the prednisone when the attack first signals, it’s gone before it starts. If I wait a couple of days I have to take a higher dose.
Prednisone is demonized by half the doctors I have consulted, and it has super bad side effects when taken for long periods. Doctors will advise NSAIDs which is great if they work for you but for me they make no difference. Colchicine works but it takes 4 or 5 days and causes diarrhea in treatment sized doses. I took colchicine prophylactically for a couple of years but still got gout sometimes so gave up on that. These days I get gout every 3 months or so, take my correct dose of prednisone (doctor approved) and have no issues with zero changes in diet. I think all of us should inform ourselves about gout and discover our personal best treatment in consultation with a doctor who we trust.
Dear Spiro.
I am 63 years old and have been taking Colchicine twice a day for seven months now. And it works, I haven’t had gout attacks for five months. But you listed Colchicine as short term medication. Am I taking it for so long now? Will I have side effects soon so I better stop taking it now?
Hi Juliana!
The majority of gout sufferers are prescribed colchicine usually to treat the gout attacks or flareups. Now if your uric acid is really high, your doctor can prescribe you in addition to a daily dose of allopurinol, a daily dose of colchicine as well. So follow your doctor’s advice cause he knows your health situation best.
Hi!
Please my right ankle used to swollen and I sometimes feel pains in my knee, toe and elbow especially midnight, so I went and have a Doppler scan and the doctor says I have osteoarthritis and they gave me medicine after taking the medication it came back to square one. Until I was told am suffering from gout. Please can you tell me which medication will be good for my gout cause am suffering the pain is too much for me?
Thanks!
Hi Stella!
Please visit your doctor and most likely your doctor will prescribe you colchicine to get rid of the pain and inflammation. Then if uric acid levels are high, your doctor may prescribe you allopurinol for long term use to control uric acid levels in your blood and avoid any future flare-ups.
Good luck!
I starting taking homeopathy… Did any one have experience with homeopathy ?
I took Colchicum C 30, I still don’t feel any effect that’s why I ask if any one here ever took.
By the way, I am Gout sufferer since 4 years ago and the attack coming and going specially when I do handheld of my 35 kg camera, I am cinematographer in Asia and Europe and I started following the diet from this site, I buy the book for my ipad, but I can not share it with my laptop ? thx
Spiro, I’m considering purchasing a uric acid test kit and have a couple of questions. I’ve read conflicting comments regarding testing oneself if prescription meds are being taken; stating you don’t really need to test yourself regularly if you’re on the gout meds. Secondly, do you have any recommendations on a test kit? Apparently no one in the US makes these test kits, so if I were to order one from say Amazon.com, it is coming from Indonesia at a price of $180 US.
Hi Brian!
From what I’ve heard and read, these kits don’t measure uric acid that accurately. Nothing will beat a blood test.I’d go with this service personally–> https://www.wellnessfx.com/
Hi Sipro,
I really appreciate your efforts to share your knowledge and experience on gout which makes you a Hero, who is trying to change the lives of others without repeating the same mistakes.
I am currently suffering an attack and my doctor didn’t prescribe me any pain killers except Divido. After having a very painful night, I went to the emergency and General Physician prescribed my Prednisone (50mg), which is a big relief for inflammation but swelling is getting reduced as per his own speed, consequently not able to wear any shoes. I wanted to know your thoughts about this.
Hi Arshad!
I don’t comment on any prescription drugs and what your doctor prescribed and why since I am not a doctor and not familiar with your unique health situation. If I were you I’d ask why they didn’t prescribe you Colchicine. I find it works the fastest to get the pain, swelling and inflammation removed.
Hi
New to your blog, a 38 yo two year gout sufferer, probably 6 acute attacks, mainly right or left big toe.
Doctor finally noted the slight hyperuricemia and recommended a low purine diet and greatly increased water consumption (from a very low level of water intake). Have been doing it for a month and now have zero alcohol as well. The target is to get uric acid down to below 6mg/dl so as to dissolve the crystals over time. Last test it was 8.3.
I want to try this dietary alone but the Dr did recommend Allopurinol (or rather the brand name it’s called in Australia but same active ingredient). Are the meds effective – the potential for increased initial acute gout attacks doesn’t sound appealing?
I never knew pain before I felt what gout is !
Hi Brian!
Yes allopurinol is very effective in keeping your uric acid levels low so you don’t suffer another gout attack. It is the most prescribed drug in the world for lowering uric acid long term.
Best of luck!
Hi Spiro,
Does allopurinol and diet go hand in hand? I mean, while on allopurinol, do we have to be as strict on diet compared to a diet control without allopurinol? Once again, thanks for your wonderful service to the gout community
Hi Partha!
If you want to eat what you want and keep your bad eating habits, even though you are taking allopurinol, your health will worsen over time especially if you suffer from gout, since you are at an increased risk of so many other gout complications like diabetes, high blood pressure, kidney stones et…Always follow a strict gout diet and eat what you want on occassion only.
Hi Spiro,
While doing research on the net, I came across your wonderful website. I have been diagnosed with gout recently and had 3 attacks in the past one year. The third attack was the most debilitating one and sent me to the ER The doctor gave me an NSAID (indomethacin), which calmed the flare down in about 3-4 days Now y faily doctor wants me to go in a regimen of 200mg allopurinol . Reading about its side affects, I a a bit concerned. Should I go for it or should I concentrate on my diet to control uric acid levels?
Hi Partha!
As always I can’t give any advice on prescription drugs since I am not a doctor and do not know enough information about your overall health and blood work metrics. Best you talk to your doctor first and propose a strict diet and measure your uric acid levels over the next few months to monitor results. See what he tells you. Best of luck!
Hi Spiro,
Should I take Colchicine and Indomethacin at the same time when I get a gout flare up?
Should I continue to take Allopurinol during a Gout Flare up?
Is Ibuprofen allowed to be used with Colchicine and Indomethacin?
Thank you.
Mark
Sorry Mark I don’t provide any advice on prescription drugs, please see your doctor for that since he knows your situation best (uric acid levels and other blood work metrics). If you have questions about foods and gout diet, I’d be happy to answer your questions.
Spiro:
Is it ok to take ginger, cinnamon and turmeric at the same time. Is there any reaction that could be bad regarding how they interact with one another?
Thank you,
John Heropoulos
Hi John!
If you are taking any medications then do consult your doctor to make sure there are no dangerous reactions but preferably take either ginger or turmeric with cinnamon since turmeric and ginger are almost the same really, maybe switch it up here and there. You shouldn’t have any reactions unless you are allergic to any of these.
Hi Spiro,
I’ve been following your website for a long time and find it very inspiring. I’ve been suffering from gout on and off for about 10 years.
I use a combination of Naproxen and Colchicine to keep it under control during an attack, which normally within a week I’m back to normal. My doctor advised me to abstain from alcohol after numerous blood tests showing liver enzyme problems. I’ve been off alcohol now for 7 seven months. Not even a problem giving it up, I found it easy. What has been happening though is confusing, I’ve been getting more frequent and severe gout attacks since stopping alcohol. Is this the body trying to expel stored gout deposits that’s making my gout worse? Thanks for reading this.
Yes Colin that is very common, as crystals deposits try to get expelled as you say, it can cause some more gout attacks during that process which can take a long time. If you are on allopurinol or other uric acid lowering medication, it shouldn’t affect you and if it does, go see your doctor.
Well at long last I’m starting to take allopurinol after seeing my doctor regarding my last post here. The dosage will start at 100mg then ramping to 300mg over the course of 6 weeks.
I hope this and your dietary advise will do the trick.
Thanks!